Top 10 Tips for Successful IVF for the First Time

To improve your chances of success with your first IVF cycle, it’s important to get good medical care, live a healthy lifestyle, and be emotionally prepared. It’s best to follow your clinic’s ovarian stimulation protocol and attend all scheduled tests and scans so medications can be adjusted before egg retrieval. Eating a diet rich in plant proteins, antioxidants, and other nutrients supports egg health and embryo quality.

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Starting your first IVF cycle can bring a wave of emotions. As the treatment involves hormone injections, scans, and procedures, it’s natural to feel overwhelmed at times. Your physical and emotional preparation plays a key role in how well your body responds.



Factors such as a balanced diet, quality sleep, healthy weight, and reduced stress levels directly influence treatment success. It's also important to understand your cycle timeline and stay informed about each phase of IVF.

While every journey is different, building daily routines around rest, nourishment, and self-care can support your outcomes. By taking small, consistent steps and staying connected with your fertility team, you place yourself in the best position for a smoother, more supported experience throughout your first IVF cycle.


IVF: An Overview

IVF allows conception through an external combination of eggs and sperm. Healthcare experts use IVF as a treatment after timed intercourse and intrauterine insemination (IUI) proves unsuccessful or inappropriate for the patient.

IVF procedure

IVF treatment involves a sequence of carefully timed steps designed to support fertilisation and implantation. Each stage plays an important role in preparing your body and selecting healthy embryos. Below is a brief overview of what typically happens during the IVF process:

  • Ovarian stimulation

You start hormone injections to support the growth of multiple ovarian follicles. Medications such as follicle-stimulating hormone (FSH) and luteinising hormone (LH) analogues are commonly used. Your healthcare expert usually monitors follicle development through scans and blood tests.

  • Egg retrieval

A final injection sets egg maturity once your follicles reach the correct size. Usually under mild sedation, your eggs are collected in a short process. This is done using a fine needle and ultrasound guidance after around 36 hours.

  • Fertilisation and embryo development

The process of fertilisation and embryo development involves combining your sperm and eggs in a laboratory. Either standard insemination or intracytoplasmic sperm injection (ICSI) is used depending on the sperm quality. Fertilised eggs are monitored for several days to track embryo growth.

  • Embryo transfer

The medical staff selects a high-quality embryo before placing it into your uterus through a soft catheter. The medical staff performs this procedure during your normal state of consciousness through a quick and painless method. You can freeze the remaining viable embryos for later use.

  • Luteal phase support

After embryo transfer, progesterone is usually given to support the uterine lining. It helps the embryo implant properly. The pregnancy test takes place 10–14 days after this period ends.


10 Best Tips for Successful IVF for the First Time

The following tips prepare your body, along with your mental state and daily activities, to enhance the success of your IVF treatment:

  • Select the appropriate fertility clinic

The clinic you choose plays a key role in your IVF success. Start by checking whether it holds a valid Human Fertilisation and Embryology Authority (HFEA) licence. You can also compare success rates for people in your age group and review recent inspection reports that highlight lab safety and quality of care.

Check the former experiences of patients by speaking with them or viewing independent review platforms. Your successful IVF case requires experts from three teams at the clinic who function as doctors, along with embryologists and counsellors who collaborate for optimal results.

Clinics running numerous IVF cycles normally develop optimised processes that tend to boost achievement rates for patients.


  • Follow a fertility-friendly diet

Food consumption directly influences both fertility capacity and reaction to IVF treatment. It’s best to include proteins, healthy fats, whole grains, and a mix of fruits and vegetables in your daily meals. Plants and certain types of fish nourish eggs along with hormones and help in embryonic development.

Also include anti-inflammatory Omega-3 fats in your diet by eating flaxseeds or consuming wild fish, which may strengthen cellular structures. A combination of leafy greens together with citrus fruits may give your body folate, which facilitates embryo implantation and thereafter promotes early development.

Avoid trans fats, sugary snacks, and processed foods, as they disrupt hormone balance. Choose water over sugary drinks, and limit caffeine intake to under 200 milligrams per day.


  • Maintain a healthy weight

Your response to IVF treatment tends to improve when you maintain a healthy weight and support hormonal balance.

How BMI affects IVF outcomes

  • Your body mass index (BMI) can influence the amount of medication you need and how your eggs develop during IVF. Studies suggest that women with a BMI between 19 and 30 often experience higher live birth rates per cycle.
  • A BMI over 30 may increase the likelihood of cycle cancellations and lower implantation rates, while a BMI below 19 could affect ovulation and reduce your chances of pregnancy.
  • It’s helpful to consider how BMI might impact your IVF journey, but remember, many factors play a role in success. Working closely with your healthcare expert can help guide the best approach for you.

Common weight management tips

  • Balanced meals: Every day, try to eat three meals that are high in nutrients like vegetables, whole grains, and lean protein.
  • Regular exercise: Aim for at least 150 minutes of moderate activity each week, like swimming or brisk walking.
  • Realistic goals: To preserve hormone stability, aim for a weekly weight change of 0.5 to 1 kg.
  • Monitor progress: Keep a simple log of your food and activities to spot patterns and make adjustments.

  • Maintain a positive mindset

Optimistic thinking helps decrease stress levels and protects the hormone equilibrium throughout your entire IVF procedure. Practising gratitude daily, along with positive self-assurance, helps build your resilience.


Building emotional support allows you to better manage the unpredictability of treatments. Here are some ways to develop a positive mindset:

  • Mindfulness practices: Try long breathing exercises or meditation sessions each morning.
  • Professional counselling: Speak with a fertility therapist to work through fears and build coping strategies.
  • Support networks: Join a local or online fertility group to share experiences and advice.
  • Creative outlets: Opt for hobbies, such as painting or cooking, to convert your anxiety into a positive activity.
  • Partner communication: Discuss feelings and expectations openly with your partner to strengthen your bond.

  • Track ovulation effectively

You observe when ovulation occurs to determine your fertile period, which guides you regarding the best moment for sexual relations and medical procedures. Here are some methods combined, which give you higher accuracy in tracking.

  • Calendar method: Record your cycle lengths for 6–12 months to estimate when ovulation occurs, typically 10–16 days before your next period.
  • Cervical mucus monitoring: Note changes in mucus texture—clear, stretchy mucus often signals peak fertility.
  • Basal body temperature: Measure your temperature every morning before rising; a rise of about 0.3–0.5 °C indicates ovulation.
  • LH urine kits: Test daily around the expected mid-cycle; a surge in luteinising hormone confirms imminent ovulation.
  • Follicle tracking: To monitor follicle growth and forecast egg release, schedule ultrasound scans on days 10–12 of your cycle.
Combining these approaches helps you confirm ovulation more reliably than any single method alone.


  • Prioritise Sleep

Your reproductive health, together with your hormone balance, depends strongly on getting sufficient rest each night. The ability to implant may decrease while egg quality deteriorates when sleep is of poor quality.

It’s best to spend 7-9 high-quality hours asleep each night. Try to keep a consistent sleep schedule, even on weekends, to stabilise your body clock. Make your bedroom cool, dark, and quiet, and avoid screens an hour before bed.



  • Take key supplements

Body systems require additional help to get ready for undergoing IVF. Supplements serve to bridge nutritional deficiencies, and they also enhance egg quality, together with hormone regulation.

You might consider taking folic acid in doses between 400–800 mcg daily, starting at least three months before treatment, as this could support your cells and reduce the risk of neural tube defects.

Other supplements that may be helpful include Vitamin D for hormone regulation and endometrial health, CoQ10 to support egg quality and energy, Omega-3 fatty acids for hormone balance and uterine lining, Myo-inositol if you have PCOS or insulin resistance, and Selenium and zinc for healthy eggs and hormone production.

However, it’s important to remember that the evidence for some of these supplements can vary. For instance, while CoQ10 may be beneficial for some, it’s not universally recommended, and excessive selenium can be harmful. Always consult with a fertility specialist before starting any supplements, as they can advise you on the best approach for your individual needs.


  • Prioritise uterine health

The likelihood of embryo implantation reaches its highest level when the endometrium is in a healthy condition. An ideal endometrium appears as a triple-line on ultrasound examinations and exhibits measurements between 7 and 8 millimetres.

You might want to wear warm clothing on your lower body while doing gentle yoga or walking, as this could help improve blood circulation and support your uterine environment. Additionally, nutrients like Vitamin E, omega-3s, and L-arginine may help improve endometrial quality and overall reproductive health.

Wearing cosy lower body clothing or soaking your feet in warm water may help regulate your menstrual cycle. Your clinic may also suggest treatments like acupuncture or an endometrial scratch procedure.


  • Limit exposure to environmental toxins

Exposure to toxic substances within food, together with plastic and chemical cosmetics disrupts hormones and produces bad effects on egg cell properties. It's best to avoid plastic containers with BPA. Glass and stainless steel are the recommended materials for storing food and drink.

Proper fruit and vegetable washing helps lower the amount of pesticide exposure. Decline the intake of highly packaged foods because they contain harmful food additives. These minor lifestyle changes help maintain hormone balance, which results in improved conditions for conception to happen.


  • Communicate openly with your fertility specialist

Clear communication with your fertility team plays a vital role in the success of your IVF cycle. From your initial consultation to the final stages of treatment, it is essential that you ask questions, share concerns, and understand each step. When you express your preferences or past experiences, your team can personalise protocols based on your medical history and emotional needs.

Inform your healthcare expert about any symptoms, emotional challenges, or unexpected issues during the cycle. IVF is a dynamic process, and early communication allows your specialist to adjust plans promptly. This collaborative approach builds trust and helps you feel more empowered and supported throughout your journey.

Your first IVF cycle requires medical appointments and full physical preparation. It's important for your body to be ready to get the best results. Combining a calm mindset, realistic goals, and regular self-care improves your chances of success. The physical and emotional preparation you put in boosts your confidence and helps you feel more at ease throughout the process.


FAQs on Top 10 Tips for Successful IVF for the First Time

  1. When is the best time to begin preparing for IVF?
    It’s best to start preparing at least three months before your IVF cycle. This allows time to support egg maturation, build up nutritional stores, and stabilise hormone levels for better treatment response.
  2. Can stress impact IVF outcomes?
    Yes. Ongoing stress raises cortisol, which may interfere with ovulation, hormone balance, and embryo implantation. Practising mindfulness and seeking emotional support can improve your overall chances.
Disclaimer: Medically approved by Dr Rohan Palshetkar, Consultant IVF Specialist, Bloom IVF, Palshetkar Patil Nursing Home, Opera House