Is personalised IVF available in all fertility centres in India?

No. It's more common in tier-1 cities and specialised IVF centres. But awareness and access are growing rapidly.

Will genetic testing harm my embryos?

Most tests like PGT are performed at the blastocyst stage using non-invasive or minimal biopsy techniques, with very low risk.

Can personalised IVF protocols improve outcomes for older individuals?

Yes. Genetic testing helps identify embryos with normal chromosomes (euploid), which is especially useful for individuals above 35, where chromosomal abnormalities are more common.

Is genetic testing during IVF safe for the embryo?

Yes, current techniques like trophectoderm biopsy at the blastocyst stage are considered safe and minimally invasive. Still, always consult your doctor about risks and benefits.

Initial genetic testing adds to the upfront cost, but it may reduce the number of failed IVF cycles, saving money overall.

Personalised IVF: How Genetic Testing Can Improve Success Rates

Personalised IVF uses genetic testing to tailor treatment to your unique biology, improving success rates and reducing risks. It helps identify the right medication, select healthy embryos, and prevent genetic conditions. Even with all the right steps, IVF isn’t always successful.

What is Personalised IVF?

Personalised IVF involves tailoring your treatment based on your individual genetic makeup and clinical profile. By analysing specific genes that affect ovarian function, hormone response, egg quality, and embryo development, your fertility team can design a protocol that works with your biology, not against it.

Think of it like a custom-made outfit designed to fit you, not the average patient.

How Genetic Testing Helps in IVF Personalisation

Genetic testing now plays a vital role in:

1. Predicting Ovarian Response

Certain genes influence how your ovaries respond to stimulation.
For example, variants in FSHR (follicle-stimulating hormone receptor) and AMH (anti-Müllerian hormone) genes can predict whether you'll be a poor or hyper responder.
This allows doctors to adjust your medication dosage early on reducing trial and error.

2. Embryo Selection

Using Preimplantation Genetic Testing for Aneuploidy (PGT-A) helps select embryos with normal chromosomal numbers.
This improves implantation rates and reduces miscarriage risk.

3. Preventing Genetic Diseases

PGT-M and PGT-SR help identify inherited conditions or structural rearrangements in embryos.
Only healthy embryos are selected for transfer.

4. Managing Recurrent IVF Failure or Miscarriage

Genetic analysis of parents (such as karyotyping or whole genome sequencing) can reveal hidden chromosomal or single-gene mutations.
Understanding this helps craft future cycles that bypass known risks.

5. Pharmacogenomics in IVF

This new area studies how your genes affect your response to medications.
It helps decide which hormone medications work best for you, and in what dosage.

Benefits of Personalised IVF Protocols

Higher success rates: Custom treatment plans reduce the likelihood of failed cycles.
Fewer side effects: By tailoring medication, your body is less likely to experience overstimulation or under-response.
Reduced costs in the long run: Although initial testing may add expense, it can lower overall IVF cycle counts.
Improved emotional wellbeing: A protocol that’s made for you can help reduce uncertainty and stress.

The Future of Personalised IVF in India

India’s fertility clinics are gradually adopting genetic testing tools to improve IVF outcomes, especially in metro cities. Here’s what’s on the horizon:

Expanded carrier screening to assess both partners for hundreds of conditions
Artificial Intelligence + Genetic data to predict best embryo and protocol match
Ethnicity-specific gene panels tailored to Indian populations

Personalised IVF protocols based on genetic testing mark a revolutionary shift in fertility care, offering hope where uncertainty once prevailed. By tailoring treatment to your unique genetic profile, doctors can now predict how your body will respond to medication, select the healthiest embryos, and significantly improve the chances of a successful pregnancy. This approach not only enhances success rates but also reduces the physical, emotional, and financial strain often associated with multiple IVF cycles.

Whether you're facing unexplained infertility, recurrent IVF failures, or a known genetic condition, personalised protocols can bring you closer to your goal with more confidence and clarity. As access to genetic testing continues to grow in India, more individuals and couples can benefit from this advanced, patient-centric approach to reproductive medicine. Speak to your fertility expert about how personalised IVF might fit into your journey, and move forward with decisions rooted in science, precision, and care.

FAQs on The Potential of Personalised IVF Protocols Based on Genetic Testing

Is personalised IVF available in all fertility centres in India?
No. It's more common in tier-1 cities and specialised IVF centres. But awareness and access are growing rapidly.
Will genetic testing harm my embryos?
Most tests like PGT are performed at the blastocyst stage using non-invasive or minimal biopsy techniques, with very low risk.
Can personalised IVF protocols improve outcomes for older individuals?
Yes. Genetic testing helps identify embryos with normal chromosomes (euploid), which is especially useful for individuals above 35, where chromosomal abnormalities are more common.
Is genetic testing during IVF safe for the embryo?
Yes, current techniques like trophectoderm biopsy at the blastocyst stage are considered safe and minimally invasive. Still, always consult your doctor about risks and benefits.
Is it expensive?
Initial genetic testing adds to the upfront cost, but it may reduce the number of failed IVF cycles, saving money overall.