In this article:
How Vitamin D Affects IVF Outcomes
If you’re going through IVF or planning to, your vitamin D status could influence how successful your treatment will be.Studies show a strong correlation between vitamin D levels and IVF success.
- Women with higher vitamin D in their follicular fluid had better embryo quality and implantation outcomes
- Each small increase in vitamin D concentration improves clinical pregnancy rates by up to 2.4 per cent
- This means that ensuring optimal levels before IVF could improve not just fertilisation but also the chances of a healthy pregnancy
Men’s Fertility and Vitamin D
Fertility is not just a female concern. Vitamin D also supports sperm health.- Sperm count and motility tend to be better in men with sufficient vitamin D levels
- Vitamin D may positively influence testosterone levels in older men, although it does not appear to have the same effect in younger males
- It aids sperm function during fertilisation, although it is not present in semen
- If your partner is also being evaluated for fertility, checking their vitamin D status could be useful
The Vitamin D and PCOS Connection
If you’ve been diagnosed with polycystic ovary syndrome (PCOS), there’s an even stronger reason to monitor your vitamin D.- As many as 85% of people with PCOS may have low vitamin D levels
- This deficiency has been linked with more severe menstrual irregularities, higher androgen levels, and reduced ovulation rates
- Low vitamin D may worsen insulin resistance, which is a key factor in PCOS-related fertility struggles
Correcting the deficiency may help restore ovulation, regulate menstrual cycles, and improve outcomes with fertility treatments
Improvements Seen with Vitamin D Supplementation in PCOS
Vitamin D may support fertility in PCOS by:- Lowering serum androgens and Anti-Müllerian Hormone (AMH) levels
- Improving endometrial thickness and structure
- Enhancing the chances of implantation and clinical pregnancy
- Improving insulin sensitivity and possibly reducing miscarriage risk
Women with PCOS who maintain normal vitamin D levels have shown higher live birth rates after ovulation induction treatments. Even a 2.5 nmol/L increase in vitamin D has been linked to a 2 per cent rise in live birth rates
The Role of Vitamin D in Preventing Pregnancy Complications
During pregnancy, your body undergoes several changes that require hormonal and immune adaptations. Vitamin D is involved in this process as well, making it worth paying attention to.- It helps regulate maternal cortisol levels, which, if uncontrolled, could affect embryonic growth
- It reduces inflammation by lowering cytokines like TNF-α and IL-6, creating a healthier environment for embryo development
- It contributes to placental function and has even shown antibacterial activity in lab studies
Your vitamin D status might seem like a small detail in your fertility journey, but it can have a significant impact. From regulating ovulation and supporting IVF outcomes to improving endometrial receptivity and reducing pregnancy complications, especially in the context of PCOS, vitamin D plays a powerful supporting role. Addressing a deficiency could not only enhance your chances of conception but also contribute to a healthier pregnancy. Before you begin or continue fertility treatment, it’s worth speaking with your doctor about checking and optimising your vitamin D levels.
FAQs on Impact of Vitamin D on Ovarian Function, Endometrial Receptivity, and Embryo Quality
- Can I get enough vitamin D through sunlight alone?
Not always. Factors like skin tone, geographical location, air pollution, and time spent indoors can limit your body's ability to synthesise vitamin D from sunlight. - Should I take vitamin D supplements if I am trying to conceive?
Consult your fertility specialist before beginning vitamin D supplementation. Just a straightforward blood test can tell whether you’re lacking vitamin D and how much your body might need. - Does vitamin D affect miscarriage risk?
Low vitamin D has been associated with increased risk of miscarriage, particularly in those with PCOS or insulin resistance. Addressing the deficiency may help lower this risk.