How Many IVF Cycles Are Normal Before Success

IVF is a journey that may require more cycles than just one attempt for a successful conception. Understanding the number of cycles considered normal, success rates across multiple attempts, and ways to improve IVF success is crucial to healthy, safe conception. With a planned approach and medical guidance, couples can lead their IVF journey with preparedness and confidence.

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In vitro fertilisation (IVF) is a viable solution for couples struggling with infertility. However, it raises an important question: how many cycles are typically required to achieve success? While some may conceive on the first attempt, many require multiple cycles due to factors such as age, lifestyle habits, underlying medical conditions, and, most importantly, the quality of sperm, eggs and the embryos formed during an IVF cycle
However, even with advanced procedures, conception is not guaranteed on the first cycle; it’s natural for couples to require multiple attempts. Understanding the average number of IVF cycles, the factors influencing the number of cycles, and tips to optimise outcomes may help couples continue their pregnancy journey with confidence.



What are the Average Success Rates By Cycles?

While IVF cycle success rates depend on multiple factors, general trends can provide useful guidance when interpreting average data. Here are the average success rates by cycles.

● First IVF Cycle

If you’re a woman under 35, the success rates of the first IVF cycle typically range between 30% and 45% per cycle.

The success rate drops to 15-30% in the 35-40 age group and to 5-10% in those over 40. The first attempt is not just a treatment cycle but also a diagnostic assessment tool as it provides valuable insights into how the body responds to stimulation, interaction of the egg and sperm through fertilisation, the quality and number of good embryos generated through the cycle, quality of the endometrium or lining of the womb to consider embryo transfer, all of which can inform future cycles. Surplus good-quality embryos may be frozen from the first cycle, thus providing future opportunities for conception via frozen embryo replacement cycle.

● Second IVF Cycle

During the second cycle, success rates generally improve because doctors now have the patient’s insights from the first cycle. Healthcare providers now adjust medication dosages, timing, or laboratory techniques to enhance embryo quality and improve implantation rates.

● Third IVF Cycle

Success rates are typically higher in the third cycle, with studies showing increases of 50-60%. By the completion of the third cycle, doctors may be using treatment protocols customised to the individual’s condition, ultimately increasing the chances of implantation and pregnancy.

● Beyond Three Cycles

Some couples may require additional cycles to achieve a safe, successful pregnancy. While per-cycle success may decline with age or with specific fertility challenges, cumulative success may increase as each cycle increases the chances of conception.

What are the Essential Tips to Improve IVF Success?

Improving IVF success involves preparing your body, understanding your fertility, and making the right reproductive-related choices. Here’s how couples can improve their chances of IVF success.

● Undergo a Fertility Test

When you undergo a fertility test before IVF, it helps detect issues that might affect treatment, such as low ovarian reserve, compromised sperm health, thyroid imbalance, endometriosis, fibroids, other structural uterine abnormalities or autoimmune disorders. Knowing your condition before starting the therapy may help your doctor tailor medication, timing, and treatment strategy more effectively.

● Follow Your Medication Schedule

Taking doctors’ prescribed medicines for IVF cycles stimulates the ovaries to produce multiple eggs, and even minor timing variations can make a difference to the response. Furthermore, routine ultrasounds and hormone tests help your specialist adjust dosages to optimise egg development. When you stay consistent with your medication and prioritise regular appointments, it supports a safe, smooth IVF process till delivery.

● Consider Preimplantation Genetic Testing (If Required)

PGT helps screen for chromosomal abnormalities, especially for women who are above 35 years or have a history of recurrent miscarriages or a family history of certain genetic mutations. While doctors don’t recommend these tests for everyone, some studies suggest that PGT may improve implantation rates and reduce the risk of failed cycles. Furthermore, knowing your condition in advance may help your doctor customise treatment and adjust medications to support successful conception.

● Adopt a Healthy Lifestyle

Lifestyle choices have a direct impact on egg quality (in women) and sperm health (in men), which ultimately affects the embryo’s growth. Consuming a balanced diet rich in folate, iron, omega-3 fatty acids, and antioxidants may help reduce oxidative stress and improve reproductive health in both men and women. Furthermore, avoiding smoking, limiting alcohol and caffeine intake, staying hydrated, and performing light to moderate exercise daily may improve your VF results.

● Prioritise Stress Management

IVF journey, from start to end, can be physically, emotionally, and mentally challenging, which may increase chronic stress in the body. When stress hormone (cortisol) levels rise, it disrupts hormone regulation, sleep, and overall well-being. Practise stress management techniques such as yoga, meditation, acupuncture, or journaling to reduce stress and balance hormone levels for optimal reproductive health.

Note: Before starting stress management techniques, consult your doctor to rule out any underlying medical conditions. Furthermore, always follow your doctor’s advice on stress-management techniques to help regulate your hormones and improve your reproductive health.

While there is no exact number of IVF cycles that guarantee success, most couples generally achieve pregnancy within 2-3 cycles. Understanding factors that influence success, maintaining realistic expectations, and following medical guidance are crucial to increasing the chances of pregnancy.

IVF can feel overwhelming, but you’re not alone. Join our IVF support group, where stories, guidance, and strength are shared daily.

FAQs on How Many IVF Cycles Are Normal Before Success


  1. Does age affect the number of cycles needed?
    Yes, women under 35 generally require fewer cycles to achieve a successful pregnancy than older women, as they have more and higher-quality eggs.
  2. When should couples consider alternative fertility treatments?
    If multiple cycles fail or egg/sperm quality is poor, doctors may suggest donor eggs, donor sperm, or other assisted reproductive technologies.
  3. Does IVF guarantee pregnancy?
    No, IVF increases the chances of conception, but it doesn’t guarantee pregnancy. Factors such as embryo quality, uterine health, hormones, and genetics contribute to IVF outcomes.
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