How Tiny Cells Begin Dividing in the First Week After Fertilisation

Fertilisation marks the beginning of a fascinating, one-week journey during which a single cell starts to multiply into many to provide the very building blocks of life. In this blog, you will see how those tiny cells grow, multiply, and get ready for the next step in becoming an embryo. You will also get to learn what is going on inside your body during this time, what you might be able to feel, and how to take care of yourself.

Pregatips
Thinking of a pregnancy might bring to mind an expanding belly or the first kick of your baby. Well, before all of that, something equally incredible happens: within hours of fertilisation, the cells inside your body begin a dramatic parade of cell division. During the first week, this almost nanotiny journey lays the foundation for everything that follows. The changes occurring inside your body are invisible to the naked eye, or the very first signs of life. It helps to learn about it all, from conception to early wake and nurture, so that your attitude can make a difference.

Let's work our way through what really happens inside your body in that first week:

What exactly happens right after fertilisation?

When the sperm and egg join, they form a zygote, a single cell with all the instructions needed to grow into a baby. Within about a day, the zygote begins to divide into more cells, first two, then four, then eight, and so on. This process is called cleavage.
After about 5 to 6 days, the group of growing cells reaches the uterus. At this stage, it's called a blastocyst. You can think of it like a tiny seed getting ready to be planted in the womb.

How quickly do the cells multiply in the first week?

Unexpectedly, cell division proceeds at a very rapid pace:
  • Day 1: Fertilised egg (also called a zygote).
  • Day 2: 2–4 cells.
  • Day 3: 8–16 cells (often called a morula).
  • Day 4–5: about 32 cells, developing into a blastocyst, which has a cavity that is filled with fluid.
  • Days 6–7: The blastocyst attaches to the wall of the uterus and begins implantation.
After the end of this week, the fertilised egg has divided several times, but it is still only approximately the size of a pinhead.

Why does this stage matter so much?

You may wonder why these cells, which are invisible to the naked eye, are so important. Here is why:
  1. Source of development: The blastocyst is about to divide into two parts: one becomes the placenta, and the other becomes the embryo.
  2. Implantation: The blastocyst must be able to anchor itself to the uterine wall for a pregnancy to proceed.
  3. Genetic health: Problems in cell development can sometimes mean that the embryo does not implant or that there is early pregnancy loss.

What symptoms might you notice in the first week?

During the early days of pregnancy, you will normally not have any noticeable pregnancy symptoms, although you may notice the following early signs:
  • Light spotting (sometimes called implantation bleeding, although that normally happens nearer to week 2).
  • Mild cramping or bloating.
  • Fatigue or changes in mood (referred to as hormonal changes).
While most people do not know they are pregnant until after their missed period, these more subtle signs may give you some hints of being pregnant.

How can you support your body during this stage?

Although it's a natural process, there are things you can do to help support early cell division and implantation:
  • Eat a well-balanced diet, full of folic acid, iron, and protein; folic acid is especially helpful in preventing congenital disabilities.
  • Avoid smoking, alcohol, and excessive caffeine; anything that would potentially interfere with implantation.
  • Be prepared to manage stress by following techniques like meditation or deep breathing; we know stress hormones can affect early pregnancy.
  • People typically have no idea how hard the body is already working, but get as much rest as you can.

When should you see a doctor?

A pregnancy test or ultrasound is usually too early within the first week. However, you should consult with a doctor if you see:
  • Heavy bleeding (more than light spotting).
  • Moderate to severe abdominal pain.
  • Signs of infection (fever, unusual discharge, strong cramps).
Similarly, a doctor can advise you if you are planning a pregnancy, suggesting preconception health checks and vitamins.

Emotional and Social Aspects: What Should You Consider?

This moment brings a variety of feelings: excitement, anxiety, and uncertainty. Here is how to handle them better:
  • Talk about your pregnancy with your partner or trusted loved one. Support during this stage can lessen the worry.
  • Be patient with yourself, even when you can’t see it, your body is doing something amazing.
  • Avoid comparing yourself to others; every pregnancy begins and develops differently.

What should you do next?

Here’s a short guide that you can remember:
  • Continue or begin prenatal vitamins that contain folic acid.
  • Eat foods that are fresh fruits, vegetables, and protein-rich foods.
  • Engage in light to moderate exercise, unless told otherwise.
  • Avoid smoking, alcohol, and recreational drugs.
  • Schedule a preconception or early pregnancy visit if you have not done so.
One week after fertilisation is invisible to the naked eye, and arguably the most important period during pregnancy. The minute cells are dividing rapidly as they travel toward and prepare for implantation. If you eat a good diet and take the rest and care for your body's needs, you create the best environment for a life to begin. Keep in mind, every single pregnancy is different; therefore, the tiniest changes that occur within you deserve to be appreciated.

Whether you’re pregnant, a new mom, or navigating postpartum, you don’t have to do it alone. Join our support group to connect, share, and support one another.

FAQs on How Tiny Cells Begin Dividing in the First Week After Fertilisation


  1. Can you confirm pregnancy in the first week after fertilisation?
    No, it is usually too soon. Most tests cannot detect pregnancy until the second week, when implantation has occurred, and the hormone has risen.
  2. Is spotting normal in the first week?
    Light spotting may happen sometimes, but heavy bleeding is something to be cautious about. In case of severe cramps or heavy bleeding, consult a doctor.
  3. How can I improve implantation chances?
    Keep yourself healthy, eat well, take folic acid, refrain from alcohol and cigarette smoke, manage stress, and, if undergoing fertility treatment, fully comply with medical advice.
Disclaimer: Medically approved by Dr Astha Dayal, Director - Obstetrics & Gynaecology, CK Birla Hospital, Gurugram