Gestational Factors That May Increase the Risk of Birth Defects

The gestational period is the time during which your baby's body develops at a rapid pace. Certain maternal health conditions, nutritional deficiencies, infections, and harmful exposures during pregnancy may increase the risk of birth defects. Our experts explain how gestational factors may affect your pregnancy outcomes.

Pregatips
Every pregnancy is different. While most babies are born healthy, some babies suffer from congenital abnormalities. Certain factors can impact a baby's development during pregnancy. These factors are called gestational factors. Some of them may even increase the chances of birth defects in babies.
The first weeks of pregnancy are critical because the brain, heart, spine, and many organs are developing at this time. However, some factors are preventable with proper antenatal care, while others are non-preventable.

Regular medical check-ups are essential for the detection of any possible problems in pregnancy.

If you are aware of the different gestational factors that may potentially cause birth defects, you would know which situations may require close monitoring and understand the importance of regular antenatal visits during pregnancy.

Common Gestational Factors That May Increase The Risk of Birth Defects

The following are the factors that may increase the risk of developmental issues in the babies:

Gestational factor
How it may affect your baby
Uncontrolled diabetes
May increase the risk of heart, brain, and spine defects
Certain infections
May interfere with normal fetal development
Folate deficiency
Raises the risk of neural tube defects
Low iodine intake
May affect brain and nervous system development
High fever in early pregnancy
May affect organ formation in some cases
Harmful medicines or chemicals
Some exposures may interfere with fetal growth
Alcohol, smoking, or recreational drugs
May affect brain and physical development

How Does Uncontrolled Diabetes During Pregnancy Affect Your Babys Development?

High blood glucose levels in early pregnancy can increase the chance of having birth defects such as heart defects, neural tube defects, brain abnormalities, and kidney abnormalities.

If you are diabetic before pregnancy or develop diabetes during pregnancy, monitoring your blood glucose levels and following your doctor’s instructions can help prevent possible complications.


Which Infections During Pregnancy May Increase The Risk?

Certain infections can cross the placenta and affect your baby's development.

These include:

  • Rubella
  • Cytomegalovirus (CMV)
  • Toxoplasmosis
  • Syphilis
  • Chickenpox in certain situations
However, simple preventive measures may help lower your risk.

How Does Low Folate & Iodine Intake Increase The Risk of Birth Defects?

Folate

Folate plays an important role in the early development of your baby's brain and spinal cord.

Low folate levels during early pregnancy may increase the risk of neural tube defects, such as spina bifida.

Good dietary sources include:

  • Green leafy vegetables
  • Lentils
  • Beans
  • Citrus fruits
  • Fortified cereals
However, your doctor may also recommend folic acid supplementation depending on your circumstances.

Iodine

If there is low iodine intake, especially during early pregnancy, the risk of impaired development of the baby's brain and nervous system increases.

Therefore, it is recommended to take iodised salt and eat a balanced diet to meet your iodine needs. Your doctor advises supplements if needed.

Which Exposures May Affect Your Baby’s Development?

Certain medicines are considered safe during pregnancy, while others are not.

Therefore, avoid starting, stopping, or changing any medicine without medical advice.

In addition, exposure to the following may increase the risk of birth defects:

  • Alcohol
  • Smoking
  • Recreational drugs
  • Certain industrial chemicals
  • Excessive radiation exposure

Does High Fever During Early Pregnancy Matter?

Certain studies suggest a persistent high fever during the first trimester has been associated with a slightly higher risk of certain birth defects.

If you develop a high fever during pregnancy:

  • Drink adequate fluids
  • Monitor your temperature
  • Consult your doctor if the fever persists or if there is a rash

Precautions To Lower the Risk

Although not all birth defects can be prevented, healthy pregnancy habits may reduce certain risks.

  • Attend all antenatal appointments
  • Eat a balanced diet rich in folate
  • Take supplements only as advised
  • Keep diabetes or other medical conditions well controlled
  • Avoid alcohol, smoking, and recreational drugs
  • Practise good hygiene to reduce the risk of infections
  • Discuss every medicine with your healthcare provider before using it.
  • Report fever, rashes, or unusual symptoms without delay
Get a medical review if you get exposed to any gestational factor that may increase the risk of birth defects in your baby. This is because early assessment can help you understand your individual risk and plan appropriate care.

Whether you’re pregnant, a new mom, or navigating postpartum, you don’t have to do it alone. Join our support group to connect, share, and support one another.

FAQs on Gestational Factors That May Increase the Risk of Birth Defects

  1. Can stress during pregnancy cause birth defects?
    Everyday stress has not been shown to cause birth defects directly. However, severe stress may affect your overall health.
  2. Are all birth defects preventable?
    No. Not all birth defects are preventable, especially if there are genetic or unknown causes.
  3. Can birth defects be detected during pregnancy?
    Many structural birth defects can be identified through routine antenatal ultrasound scans and other prenatal screening or diagnostic tests.
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