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The Connection Between Progesterone and “Pregnancy Brain”

Hormonal changes are inevitable when you are pregnant. They may also bring some unpleasant side effects with them. Progesterone is one such vital hormone that may affect your brain’s function, along with supporting your baby’s growth. It is also known as pregnancy brain. It makes you susceptible to experiencing forgetfulness or brain fog during pregnancy. The good thing is that it is only temporary, and you can manage it more effectively once you understand its connection to your progesterone levels.

Pregatips
pregnancy brain
You may notice that you forget things easily if you are pregnant. You may go to the room, but forget why you came in there the moment you enter. You may also not find the correct word to describe something, even if it's at the tip of your tongue. It is also referred to as pregnancy brain, which can be frustrating.
Please remember that it is not your fault, but simply a biological reaction to the pregnancy hormones, called progesterone. Learning why it happens and how to curb it can help you stay sharp during pregnancy.


What Exactly Is “Pregnancy Brain”?


Pregnancy brain is not a myth, but a condition in which you may undergo a cognitive shift in your thinking abilities. The following signs characterise it:

  • Forgetting small tasks or appointments
  • Trouble focusing or concentrating
  • Feeling mentally “foggy” or slower than usual
  • Being more emotional or easily distracted
According to research, almost 80% of pregnancy cases report some sort of memory change or loss of attention span. However, these are only temporary changes and will return to normal after the baby is delivered.


What Does Progesterone Do During Pregnancy?


Progesterone plays a crucial role in numerous major functions during pregnancy.

  • It prepares the uterus for implantation
  • It supports the development of the placenta
  • It relaxes your muscles and prevents early contractions
  • It helps develop breast tissue for milk production
Progesterone levels rise to nearly 10 to 20 times the normal range throughout pregnancy. This surge may affect your reproductive system and brain functions that support memory, mood and focus.


How Does Progesterone Affect Your Brain Function?


Progesterone acts as a neuroactive steroid, meaning it can directly affect brain activity.

  • Progesterone affects GABA (gamma-aminobutyric acid), a brain chemical that helps you stay calm. So, you may feel relaxed, but it may also slow down your mental alertness.
  • Higher progesterone levels can cause drowsiness or poor sleep quality in later stages of pregnancy. Lack of rest affects your memory and concentration.
  • Increased blood flow to the uterus and baby means less oxygen supply for your brain at times, which may contribute to mild confusion or brain fog.
  • Progesterone also interacts with mood-regulating hormones, so that you may feel emotional, forgetful, or mentally drained.


Is “Pregnancy Brain” the Same for Everyone?


The severity of forgetfulness is different in every case, so you may feel it is more pronounced compared to others. You may notice it more in the second or third trimester when hormonal changes are at their peak levels.
You may notice pregnancy brain more due to the following factors:

  • Lack of sleep
  • Stress and anxiety
  • Nutrient deficiencies (like low iron or vitamin B12)
  • Juggling multiple responsibilities at once


Can Progesterone Have Positive Effects on Your Brain Too?


While forgetfulness is one thing, progesterone also has a positive effect on your brain.

  • It promotes the growth of new brain cells
  • It supports brain healing and reduces inflammation
  • It helps balance mood and reduce anxiety


What Can You Do to Cope with Pregnancy Brain?


You can take control of certain aspects of your pregnancy, such as making lifestyle changes for the better.

  • Prioritise Sleep

Try to get at least 7 to 8 hours of quality sleep every night. If you find it difficult to sleep at night, take short naps during the day.

  • Eat Brain-Boosting Foods

Eat foods rich in omega-3 fatty acids, iron and vitamin B12. Fish, leafy greens, eggs, and nuts are naturally rich in these vital nutrients. They will improve your brain function and help you concentrate.

  • Stay Active

You can support blood circulation in your body by walking or doing other mild exercises.

  • Keep Notes and Reminders

Track your appointments, medications, or any other important information in your notebook or on an app on your phone.

  • Manage Stress

When it comes to stress, do not underestimate the power of deep breathing or meditation. They can help you think clearly.


When Should You Talk to Your Doctor?


The following symptoms may indicate a serious issue that requires medical attention.

  • Persistent confusion or disorientation
  • Severe mood swings or depression
  • Difficulty managing daily tasks
  • Ongoing sleep issues


Emotional and Social Aspects of Pregnancy Brain


Forgetting things can easily make you feel frustrated if you like to keep everything organised. However, this is normal, so it is okay to ask for help. Talk about your feelings. You may feel embarrassed to admit it to your loved ones or your partner, but they can give you an extra hand. You may find it helpful if you take these forgetful moments lightly and laugh them off.


What to Do Next: A Quick Checklist


  • Keep a daily planner or use a reminder app to stay organised
  • Eat a balanced diet
  • Sleep and rest whenever possible
  • Stay hydrated
  • Talk to your doctor about vitamins or supplements
  • Be kind to yourself and remember that it will pass
Pregnancy brain does not make you careless; it simply indicates that your body is adjusting to hormonal changes. So, forgetting things from time to time is okay if it does not affect your routine. You can attribute this condition to elevated progesterone levels. At the same time, it is necessary for your baby’s growth and also for you to prepare for motherhood. Your mental clarity will improve with proper rest and good eating habits.

FAQs on The Connection Between Progesterone and “Pregnancy Brain”

  1. Does progesterone cause memory loss during pregnancy?
    High levels of progesterone can slow down brain functions, but they do not cause memory loss directly. This condition may lead to brain fog.
  2. How long does pregnancy brain last?
    Your condition may improve within a few months after you deliver the baby, as hormone levels return to normal levels and you get better sleep.
  3. Can supplements or vitamins help with pregnancy brain?
    Omega-3, iron and B-complex vitamins are crucial for your brain health. You can consult your doctor for the specific nutrients needed in your case before starting any supplement.
Medically Reviewed By:
Medically approved by Dr Aastha Gupta, Senior IVF consultant & fertility expert, Obs/ Gynae at Delhi IVF, New Delhi
Times Future of Maternity 2026 | India's Largest Maternity Ecosystem Gathering
Times Future of Maternity 2026 | India's Largest Maternity Ecosystem Gathering