What Are Epstein Pearls in Newborns? Are They Normal?

Parents may wonder about the tiny white bumps they notice in their newborn’s mouth. In this guide, our expert explains why these spots are called Epstein pearls, why they appear, whether they need treatment, how long they last, and when parents should seek medical advice.

Pregatips
Epstein pearls in newborns
Noticing unusual spots inside your baby’s mouth can be worrying, especially during the first few weeks. You may wonder if they are linked to feeding, teething, or an infection. Epstein pearls are one possible reason for these small spots and are usually nothing to worry about. Knowing what they look like and how they differ from other mouth changes can make them easier to recognise.
We spoke with Dr Manish Mittal, Senior Consultant – Paediatrics, Cocoon Hospital, Jaipur, to understand more about Epstein pearls in newborns.

What Are Epstein Pearls in Newborns?

Epstein pearls are tiny white or yellowish bumps that can appear inside a newborn’s mouth.

They are small cysts filled with a protein called keratin and are usually found:

  • Along the baby’s gums
  • On the roof of the mouth
  • Near the area where the hard and soft palate meet
Epstein pearls in newborns2

What Do Epstein Pearls Look Like?

Epstein pearls usually look like:

  • Small, round bumps inside the baby’s mouth
  • White, cream, or yellowish in colour
  • Only a few millimetres in size
  • Firm to the touch rather than soft
  • Similar to tiny teeth or leftover milk
  • Easy to notice when the baby opens their mouth

Why Do Newborns Get Epstein Pearls?

Epstein pearls form naturally during a baby’s development before birth. As the mouth develops, some cells can become trapped beneath the surface and form these tiny bumps. There is nothing parents can do to prevent them, and they are not caused by feeding or poor hygiene.

Are Epstein Pearls Normal in Newborns?

Yes, Epstein pearls are normal and harmless in most newborns. They are quite common and usually do not bother the baby. They are not linked to serious health problems and generally do not affect the baby’s daily activities.

Do Epstein Pearls Affect Breastfeeding or Bottle-Feeding?

“Epstein pearls are harmless and usually do not cause pain. Babies can continue breastfeeding or swallowing normally without discomfort.”

  • Dr Manish Mittal, Senior Consultant – Paediatrics, Cocoon Hospital, Jaipur
If your baby is having trouble feeding or repeatedly refusing feeds, speak with a paediatrician. The cause may be unrelated to Epstein pearls.

Epstein Pearls vs Oral Thrush: What’s the Difference?

White spots in a baby’s mouth can sometimes be confused with oral thrush.

Epstein Pearls
Oral Thrush
Small, white or yellowish bumps
White patches or coating
Usually found on the gums or roof of the mouth
Often appears on the tongue, inner cheeks, gums, or roof of the mouth
Firm and separate from nearby tissue
May look like creamy patches
Usually do not bother the baby
May sometimes make feeding uncomfortable
No treatment is usually needed
May need antifungal treatment prescribed by a doctor

How Long Do Epstein Pearls Last?

Dr Manish Mittal says that Epstein pearls usually disappear on their own within a few weeks after birth. You may notice them becoming smaller before they completely go away. They do not need to be squeezed, scraped, or treated. If the spots persist longer than expected or start to look different, have your baby checked by a paediatrician.

Do Epstein Pearls Mean My Baby Has a Dental Problem?

No, Epstein pearls are not a dental problem. They are a normal finding in a newborn’s mouth and are different from natal teeth, which are actual teeth present at birth.

If you are unsure whether a white bump is an Epstein pearl or a tooth, your baby’s paediatrician or dentist can take a quick look and confirm what it is.

What Can Parents Do at Home?

Dr Manish Mittal says that most parents do not need to do anything for Epstein pearls. Leaving them alone is usually the best approach while they naturally clear.

  • Feed your baby as usual
  • Do not pop, squeeze, or scrape the bumps
  • Avoid applying oils, medicines, or home remedies

When Should Parents See a Doctor?

Consider contacting your baby’s paediatrician if:

  • Your baby is having trouble feeding or refusing feeds
  • Your baby develops a fever or seems unusually unwell
  • The spots spread or appear in several areas of the mouth
  • You notice bleeding or fluid coming from the spots
  • The spots remain for longer than expected
  • You are unsure whether the spots are Epstein pearls or another mouth condition
Seeing white bumps in your newborn’s mouth can be concerning, especially if you have never seen them before. Epstein pearls are usually nothing to worry about and tend to settle naturally. You can continue your baby’s normal feeding routine without making changes. If something about the spots seems unusual, ask your paediatrician for guidance.

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FAQs on What Are Epstein Pearls in Newborns? Are They Normal?

  1. Are Epstein pearls contagious?
    No. Epstein pearls are not contagious because they are not caused by an infection. Your baby cannot spread them to another baby through feeding, touching, or close contact. They develop naturally during mouth development before birth.
  2. Can Epstein pearls interfere with teething later?
    No. Epstein pearls do not interfere with the normal development or eruption of baby teeth. They are separate from the teething process and usually disappear well before your baby’s first teeth begin to appear.
  3. Do Epstein pearls leave scars?
    No. Epstein pearls usually disappear without leaving scars or marks. Once they clear, the baby’s mouth generally looks normal again, and there is usually no lasting change to the gums or palate.
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